Universität Leipzig / Lehrstuhl für Kardiologie
 
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Universität Leipzig / Lehrstuhl für Kardiologie
 
 
PD Dr. rer. nat. habil. Volker Adams / Curriculum vitae
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Education

1980-1985   Study of biology at the University of Konstanz, Germany
1985-1986   Finishing the diploma thesis at the University of Konstanz, Faculty of Biology, Department of Biochemistry (Prof. Dr. med. Pette) under the supervision of Prof. Dr. med. D. Brdiczka. The title of the thesis was: Hormonal regulation of hexokinase and its binding to the outer mitochondrial membrane.
1986-1989   PhD student at the University of Konstanz, Faculty of Biology, Department of Biochemistry (Prof. Dr. med. Pette) under the supervision of Prof. Dr. med. D. Brdiczka. The title of the PhD thesis: Isolation and characterization of contact sites between the inner and outer mitochondrial membrane in different tissues, and the importance of the contact sites in the regulation of energy metabolism.
Juli 2001   Habilitation for Molecular Cardiology at the University of Leipzig, Medical Faculty. Title: Molecular and structural alterations in skeletal muscle of patients with chronic heart failure.
 
Research Experience

Jan '90 - Juli '91   Postdoctoral Fellow at the Institute of Molecular Genetics Baylor College of Medicine, Houston, Texas (Prof. Dr. E.R.B. McCabe).

Research interest:
  1. Cloning and molecular characterization of the human glycerol-kinase gene.
  2. Characterization of the hexokinase binding to the mitochondrial outer membrane - structure function analysis to identify a sequence motif in the hexokinase protein essential for the binding to the pore protein in the mitochondrial membrane.
Juli '91 - Nov '92   Research associated at the Institute of Molecular Genetics Baylor College of Medicine, Houston, Texas (Prof. Dr. E.R.B. McCabe).

Research interest:
To establish and manage a core facility for primer synthesis and sequence analysis for the Mental Retardation Center at the Baylor College of Medicine, Houston TX. USA.
Nov '92 - Okt '95   Substitutional head of the research laboratory at the Institute of Clinical Pathology, University Hospital Zürich/Switzerland (Prof. Dr. med. J. Briner; Prof. Dr. med Ph. Heitz).

Research interest:
  1. To establish molecular methods (PCR, in situ hybridization, in situ PCR) for the detection of specific viruses in pathological formalin-fixed tissue samples.
  2. Development of a new automated method to detect and type human papillomavirusis
  3. Establishing a PCR detection method for chromosomal translocations for the Ewings-Sarcoma, starting with paraffin embedded tissue material (collaboration with the Children's Hospital of Zürich).
since
Nov '95
  Head of the Research Laboratory in Cardiology at the Heart Center Leipzig (Director: Prof. Dr. med. G. Schuler).
At the beginning the building up of a research facility for the Department of Cardiology was the main task (first 2-3 month).

Research interest:
  1. Molecular alterations in the skeletal muscle and endothelial cell layer of patients with chronic heart failure. Impact of exercise training on these alterations.
  2. Impact of exercise training on mobilization of endothelial progenitor cells (EPCs) in patients with chronic heart failure, healthy adults and children. Impact of adipokines of on EPC function and analysis of the signaling pathway.
  3. Regulation of the anabolic/catabolic pathways in the skeletal muscle of patients with chronic heart failure to understand muscle wasting. Impact of exercise training on these alterations.
  4. Molecular alteration leading to aortic valve stenosis and the impact of exercise training in the setting of primary and secondary prevention in a suitable animal model.
  5. Using an Angiotensin II infusion animal model (ApoE mouse) to study the pathophysiology of an abdominal aortic aneurysm and the impact of exercise training in the setting of primary prevention.
  6. Impact of exercise training (primary and secondary prevention) on diaphragmatic alterations in animals with chronic heart failure.
  7. Impact of exercise training on functional properties of high density lipoprotein in patients with chronic heart failure or obese children.
  8. Impact of different exercise training modalities on skeletal muscle alterations and changes in the vascular system in the setting of diastolic heart failure (heart failure with preserved ejection fraction, HFpEF).
 
Awards

Award for the best oral presentation (Meeting of the working group Rehabilitation and Exercise Physiology of the European Society of Cardiology, Bergen/Norway; 5.May 2001)

Presidents lecture at the American College of Sports Medicine (ACSM), 2006 in Denver, CO, USA. Title of the talk: Impact of Exercise on Endothelial Dysfunction and Myocardial Perfusion.

Hufeland-Preis (prestiges price in the field of prevention and rehabilitation), March 2009
 
Member of Editorial Boards and other Activities

Editorial duties
  • Editor of the European Journal of Preventive Cardiology
  • Editor of the Journal of Cachexia, Sarcopenia and Muscle Wasting


Other activities
  • Chair of the nucleus "Basic and Translational Science" of the European Association for Cardiovascular Prevention and Rehabilitation (EACPR) (2011-2012)
  • Chair of the scientific program committee (CPC) for the annual EuroPrevent congress of the European Association for Cardiovascular Prevention and Rehabilitation (EACPR) (2011-2013)
 
Leipzig, 08.10.2014


Dr. Volker Adams
 
Universität Leipzig / Lehrstuhl für Kardiologie / Mitarbeiter
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Universität Leipzig / Lehrstuhl für Kardiologie